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Metabolic & Incretin · Mitochondrial-derived peptide · 16 aa
MOTS-c
Written in mitochondrial DNA.
A 16-amino-acid peptide encoded by the mitochondrial genome, supplied lyophilized for research.
≥99% HPLC /Lot-traceable/Ships today
In stock Dispatched same day on orders placed before 12pm MST
99% purityHPLC verifiedBatch COA USA manufactured
Size
$80
$8/mg
Lab-tested99.31% purity · latest tested lot · lot MC-260421 · Freedom Diagnostics, 06/09/2026 · View certificate · Verify at the lab (code Noxa2606080374)
Add ons
Required for reconstitution · Pharmaceutical grade · 0.9% benzyl alcohol
A 10 mg vial takes about 3 mL — one 30 mL bottle covers about 10.
Want this size when it lands? Email info@metrapeptides.com and we'll tell you the day it does.
Ordering in volume? Ask us for a quote before you order.
Same-day dispatch on orders placed before 12pm MST.
Free shipping over $300. Every vial ships with its lot certificate.
Why this one
Most peptides come from the nuclear genome. This one doesn't — MOTS-c is transcribed from mitochondrial DNA itself, which is why it sits at the centre of work on how mitochondria signal their state to the rest of the cell.
Used in AMPK-linked signalling assays, mitochondrial-nuclear communication studies, and metabolic stress models in cultured cells. A reference compound for retrograde signalling.
Where it shows up in the literature
Retrograde signallingCommunication between mitochondrial state and nuclear gene expression.
AMPK pathwayActivation of AMPK-linked metabolic signalling in cell models.
Metabolic stressCellular behaviour under glucose restriction and related stressors.
Short ORF biologyCharacterisation of open reading frames within mitochondrial DNA.
Specifications
- Compound
- MOTS-c
- Presentation
- 10 – 40 mg
- Class
- Mitochondrial-derived peptide · 16 aa
- Form
- Lyophilized powder in a sealed vial
- Purity
- ≥ 99% HPLC
- Storage
- 2–8°C sealed
- Origin
- USA, GMP facility
Lot-specific identity, purity, net content and endotoxin figures are stated on the certificate of analysis supplied with each vial.
Handling
Store sealed vials at 2–8°C for short-term use, or at −20°C for long-term storage, and protect from light. Reconstitute with the diluent your protocol specifies; bacteriostatic water is the common choice where a vial will be entered more than once.
Allow refrigerated material to reach room temperature before opening, and avoid repeated freeze-thaw cycles once in solution.
Certificate of analysis
Every lot is tested by an independent ISO-accredited laboratory. The lot number on your vial resolves at the testing laboratory directly, so the purity figure never has to come from the party selling it to you.
Open the COA libraryResearch use only. MOTS-c is supplied strictly for research, laboratory and analytical use. It is not for human or veterinary consumption in any form, is not a drug, dietary supplement, cosmetic or medical device, and is not intended to diagnose, treat, cure or prevent any disease. Nothing on this page constitutes a medical claim, a treatment recommendation or a dosing protocol. Purchasers must be 21 or older and must handle all material in compliance with applicable federal, state and local law. Read the full disclaimer.
